About 3 results found for searched term "Lonidamine" (0.157 seconds)
Cat.No. | Name | Target |
---|---|---|
M1923 | Lonidamine | CFTR |
AF 1890;Diclondazolic Acid; DICA | ||
Lonidamine (AF-1890) is a novel CFTR open channel blocker with an IC50 of 0.85 mM, which inhibits aerobic glycolysis in cancer cells. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki=2.5 μM). | ||
M42433 | PROTAC HK2 Degrader-1 | Others |
PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide as a CRBN ligand-linked PROTAC. | ||
M42878 | H2-Gamendazole | Others |
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research. |
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