About 2 results found for searched term "Lonidamine" (0.111 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1923 | Lonidamine | CFTR |
| AF 1890；Diclondazolic Acid; DICA | ||
| Lonidamine (AF-1890) is a novel CFTR open channel blocker with an IC50 of 0.85 mM, which inhibits aerobic glycolysis in cancer cells. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki=2.5 μM). | ||
| M58968 | Mito-Lonidamine | Mitochondrial Related |
| Mito-LND | ||
| Mito-Lonidamine (Mito-LND) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-Lonidamine inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells. | ||
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