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 About 3 results found for searched term "Lonidamine" (0.13 seconds)

Cat.No.  Name Target
M1923 Lonidamine CFTR
AF 1890;Diclondazolic Acid; DICA
Lonidamine (AF-1890) is a novel CFTR open channel blocker with an IC50 of 0.85 mM, which inhibits aerobic glycolysis in cancer cells. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki=2.5 μM).
M42433 PROTAC HK2 Degrader-1 Others
PROTAC HK2 Degrader-1 is a PROTAC consisting of Lonidamine as a target protein Hexokinase 2 (HK2) inhibitor and Thalidomide as a CRBN ligand-linked PROTAC.
M42878 H2-Gamendazole Others
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research.



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