About 7 results found for searched term "Lipopolysaccharides" (0.123 seconds)
Cat.No. | Name | Target |
---|---|---|
M9524 | Lipopolysaccharides | Animal Modeling |
LPS | ||
Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. | ||
M1487 | D-Galactosamine hydrochloride | Animal Modeling |
D(+)-Galactosamine hydrochloride | ||
D-Galactosamine hydrochloride is usually used with lipopolysaccharides (LPS) to induce models of acute hepatic failure (LPS/D-GalN-induced liver injury, hepatitis) for therapeutic research. | ||
M5105 | MD2-TLR4-IN-1 | TLR |
MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. | ||
M22485 | Recombinant Human CD14 (HEK293, C-6His) | Cytokines and Growth Factors |
Monocyte Differentiation Antigen CD14 | ||
Recombinant Human CD14 is produced by Mammalian expression system and the target gene encoding Thr20-Cys352 is expressed with a 6His tag at the C-terminus. CD14 is a cell surface glycoprotein that is preferentially expressed on monocytes/macrophages. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a pattern recognition receptor that binds lipopolysaccharides (LPS) and a variety of ligands derived from different microbial sources. | ||
M44897 | Isophysalin G | Others |
Isophysalin G is a steroid that inhibits NO production induced by Lipopolysaccharides in macrophages with an IC50 of 64.01 μM. | ||
M49393 | Zosurabalpin | Antibiotic |
Abx MCP; RG6006 | ||
Zosurabalpin, a novel antibiotic targeting lipopolysaccharide transporters, inhibits the exocytosis of endotoxin lipopolysaccharides synthesized by carbapenem-resistant Acinetobacter baumannii (CRAB), leading to the death of CRAB due to high intracellular lipopolysaccharide concentration. | ||
M56442 | SB 706504 | p38 MAPK |
SB 706504 is a potent p38 MAPK inhibitor that inhibits Lipopolysaccharides-stimulated inflammatory gene expression in macrophages in chronic obstructive pulmonary disease (COPD). |
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