About 12 results found for searched term "Leukotriene D4" (0.882 seconds)
Cat.No. | Name | Target |
---|---|---|
M58025 | Leukotriene D4 | Others |
Leukotriene D4 | ||
M2594 | Montelukast sodium | IL Receptor/Related |
Montelukast sodium selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1. | ||
M2733 | GSK2190915 | Lipoxygenase |
AM-803, Fiboflapon | ||
GSK2190915 (AM803), a potent FLAP inhibitor, prevents the synthesis of leukotrienes and 5-oxo-ETE, with IC50 of 76 nM for inhibition of LTB4 in human blood, provides treatment for asthma. | ||
M8021 | SC 22716 | Others |
Cell-permeable leukotriene A4 (LTA4) hydrolase inhibitor that suppresses LTB4 production. | ||
M8140 | REV 5901 | Others |
Leukotriene D4 receptor antagonist. | ||
M21111 | LYS-006 | Aminopeptidase |
LTA4H-IN-1 | ||
LYS-006 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with IC50 of 2 nM. LYS-006 can be used for the research of inflammatory and autoimmune disorders, including ulcerative colitis and NASH. | ||
M28676 | Etalocib | Leukotriene Receptor |
LY293111; VML 295 | ||
Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis. | ||
M29132 | CP-195543 | Leukotriene Receptor |
CP-195543 is a potent, selective and orally active leukotriene B4 (LTB4) receptor antagonist with IC50s of 6.8, 37.0 nM for human neutrophils and murine spleen membranes, respectively. CP-195543 blocks CD11b up-regulation. CP-195543 inhibits LTB4-mediated neutrophil infiltration. | ||
M31252 | 8,11,14-Eicosatriynoic acid | Others |
8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandin, leukotriene biosynthesis, and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenase (COX)and 5-lipoxygenase (5-LO) with IC50 values of 0.46 μM, 14 μMand 25 μM, respectively. | ||
M54833 | LYS006 hydrochloride | Aminopeptidase |
LYS-006 hcl | ||
LYS-006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with IC50 of 2 nM. LYS-006 hydrochloride can be used for the research of inflammatory and autoimmune disorders, including ulcerative colitis and NASH. | ||
M56307 | CP-96021 | Platelet-activating Factor Receptor |
CP-96021 is a potent and orally available leukotriene D4 (LTD4 Ki=34 μM) / platelet activating factor (PAF Ki=37 μM) receptor antagonist. | ||
M56230 | CP-96021 hydrochloride | Leukotriene Receptor |
CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively. |
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