About 1 result found for searched term "LCL161" (0.341 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4801 | LCL161 | IAP |
| LCL-161 | ||
| LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). LCL161 enhanced the proapoptotic effects of nilotinib and PKC412, against leukemic disease in vitro and potentiated the activity of both kinase inhibitors against leukemic disease in vivo. | ||
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