About 1 result found for searched term "JZP-MA-11 " (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28794 | JZP-MA-11 | MAGL |
| JZP-MA-11 is a positron emission tomography (PET) ligand targeting the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. JZP-MA-11 can cross the blood-brain barrier (BBB). [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP). | ||
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