About 1 result found for searched term "JW 74" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6855 | JW 74 | Wnt/beta-catenin |
| JW 74 is a wnt pathway inhibitor, with an IC50 of 420 nM. JW 74 targets the β-catenin destruction complex (GSK-3 beta /AXIN/APC). JW 74 increases AXIN2 and decreases active β-catenin levels in colorectal cancer (CRC) cells. | ||
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