JNK-1-IN-1 - Search Results | AbMole BioScience

About 7 results found for searched term "JNK-1-IN-1" (0.142 seconds)

Cat.No.	Name	Target
M42128	JNK-1-IN-1	JNK
	JNK-1-IN-1 is a JNK-1 inhibitor.
M9388	Tanzisertib	JNK
	CC-930
	Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
M30350	E6201	MEK
	ER-806201
	E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosphorylation with an IC50 value of 5.2 nM, MKK4-induced JNK phosphorylation with an IC50 value of 91 nM, and MKK6-induced p38 MAPK phosphorylation with an IC50 value of 19 nM. Anti-tumor and anti-psoriasis efficacy.
M42123	JNK-IN-12	JNK
	JNK-IN-12 is a mitochondrial-targeted JNK inhibitor (IC50=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125.
M42126	JNK-1-IN-2	JNK
	JNK-1-IN-2 is a JNK-1 inhibitor (IC50: 33.5 nM).
M52816	JIP-1(153-163)	JNK
	JIP-1(153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide).
M55643	SKLB-163	Apoptosis
	SKLB163
	SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis.