About 1 result found for searched term "JI6 " (0.118 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30706 | JI6 | FLT3 |
| JI6 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits JAK3 and c-Kit, with IC50s of ∼250 and ∼500 nM, respectively. JI6 can be used for the research of acute myeloid leukemia. | ||
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