About 5 results found for searched term "Irinotecan" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2089 | Irinotecan Hydrochloride Trihydrate | Topoisomerase |
| Campto, CPT-11 | ||
| Irinotecan hydrochloride trihydrate is a potent inhibitor of DNA topoisomerase I. | ||
| M4465 | Irinotecan | Topoisomerase |
| (+)-Irinotecan; CPT-11; VAL-413 | ||
| Irinotecan is an inhibitor of Topoisomerase I, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Irinotecan inhibits the growth of LoVo and HT-29 cells, with IC50s of 15.8 ± 5.1 and 5.17 ± 1.4 μM, respectively. | ||
| M5711 | Irinotecan hydrochloride | Topoisomerase |
| CPT-11 HCl | ||
| Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor. Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. | ||
| M57715 | Irinotecan-d10 Hydrochloride | Others |
| Irinotecan-d10 Hydrochloride | ||
| M56623 | SN-38 glucuronide | Metabolite/Endogenous Metabolite |
| SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. | ||
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