About 3 results found for searched term "ISRIB" (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7425 | trans-ISRIB | PERK |
| ISRIB (trans) | ||
| trans-ISRIB is a integrated stress response (ISR) inhibitor. | ||
| M9242 | ISRIB | PERK |
| ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM. | ||
| M29296 | 2BAct | Eukaryotic Initiation Factor |
| 2BAct is a highly selective, and orally active eIF2B (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct is able to penetrate the central nervous system (CNS). 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB. | ||
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