About 3 results found for searched term "IQ-1S" (0.133 seconds)
Cat.No. | Name | Target |
---|---|---|
M8946 | IQ-1S | JNK |
IQ-1 | ||
IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. | ||
M22462 | Recombinant Human UBE2D1 (E.coli, N-GST) | Cytokines and Growth Factors |
Ubiquitin-conjugating Enzyme E2 D1 | ||
Recombinant Human UBE2D1 is produced by E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus. Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. | ||
M55647 | (R)-NX-2127 | BTK |
compound 28 | ||
(R)-NX-2127 (compound 28) is a first-in-class, orally bioavailable Bruton’s Tyrosine Kinase (Btk) degrader. (R)-NX-2127 mediates the degradation of transcription factors IKZF1 and IKZF3 through molecular glue interactions with the cereblon E3 ubiquitin ligase complex. NX-2127 degrades common BTK resistance mutants, including BTKC481S. |
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