About 3 results found for searched term "INF200" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42021 | INF200 | NLR |
| INF200 is a sulfonylurea-based inhibitor of NLRP3 and NLRP3-mediated pyroptosis. | ||
| M28373 | (±)-BI-D | HIV Protease |
| (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site. IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) [1] Target: integrase inhibitor in vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells . | ||
| M28437 | MBX2329 | Anti-infection |
| MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains. | ||
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