About 7 results found for searched term "IC265" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49932 | IC265 | Syk |
| IC265 is a splenic tyrosine kinase (Syk) inhibitor that can be used in studies related to immune system and eye diseases. | ||
| M6268 | Varenicline | AChR/AChE |
| CP 526555 | ||
| Varenicline (CP 526555) is a selective α4β2 nicotinic receptor partial agonist, it stimulates nicotine receptors more weakly than nicotine itself does. | ||
| M6392 | AC 265347 | Calcium-sensing Receptor |
| AC 265347 is a calcium-sensitive receptor (CaSR) agonist and orthosteric modulator (auto-PAM) with a functional affinity (pKB) of 5.1.AC 265347 is used in the study of hyperparathyroidism and related disorders. | ||
| M20984 | Varenicline dihydrochloride | AChR/AChE |
| Chantix, Champix | ||
| Varenicline (CP 526555, Chantix, Champix) dihydrochloride is a potent, partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR with EC50 of 2.3 μM and 55 μM, respectively. Varenicline dihydrochloride is a potent, full agonist of α7 nAChRs with EC50 of 18 μM. Varenicline is a prescription medication used for smoking cessation. | ||
| M22180 | DSM265 | DHODH |
| DSM265 is a long-acting inhibitor of Plasmodium falciparum dihydroorotic acid dehydrogenase (PfDHODH) with an IC50 value of 8.9 nM. In addition, DSM265 inhibits the growth of Pf3D7 with an EC50 value of 4.3 nM. | ||
| M29657 | IRAK4-IN-6 | IRAK |
| IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma. | ||
| M29749 | TP0597850 | MMP |
| TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min). | ||
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