About 3 results found for searched term "I-287" (0.178 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3213 | Meclizine dihydrochloride | Histamine Receptor |
| Meclozine dihydrochloride; NSC28728 | ||
| Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties, also an agonist ligand for mCAR (constitutive androstane receptor) and an inverse agonist for hCAR. Phase2. | ||
| M30686 | TPI-287 | Microtubule |
| Abeotaxane | ||
| TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain. | ||
| M49643 | I-287 | PAR |
| I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. | ||
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