About 10 results found for searched term "I-152" (0.072 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3882 | Netupitant | Neurokinin Receptor |
| CHEBI441603, CID6451149, D05152 | ||
| Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM. | ||
| M5516 | Ciclesonide | GCR |
| Ciclesonide, Alvesco, Omnaris, RPR251526, Zetonna | ||
| Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. | ||
| M7387 | TCS 5861528 | TRP Channel |
| Chembridge-5861528 | ||
| TCS 5861528 (Chembridge-5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively. | ||
| M9032 | ZINC00881524 | ROCK |
| ZINC00881524 is a potent and selective ROCK inhibitor. | ||
| M11249 | (+)-Enitociclib | CDK |
| (+)-BAY-1251152; (+)-VIP152 | ||
| (+) -enitociclib ((+) -bay-1251152) is an enantiomer of Bay-1251152 with optical rotation of (+). (+) -enitociclib is a potent selective CDK9 inhibitor with an IC50 of 3 nM. (+) -enitociclib has antitumor activity. | ||
| M21177 | (-)-Enitociclib | CDK |
| (-)-BAY-1251152; (-)-VIP152 | ||
| (-)-Enitociclib ((-)-BAY-1251152) is an enantiomer of BAY-1251152 with a (-) spin. BAY-1251152 is a potent and highly selective inhibitor of cell cycle-dependent protein kinase (PTEF/CDK9). | ||
| M27770 | Nemorubicin | DNA/RNA Synthesis |
| Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243 | ||
| Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity. | ||
| M28667 | (±)-Enitociclib | CDK |
| (±)-BAY-1251152; (±)-VIP152 | ||
| (±)-Enitociclib ((±)-BAY-1251152) is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. | ||
| M42731 | I-152 | Keap1-Nrf2 |
| I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). | ||
| M54221 | SEB Domain (152-161) | Others |
| SEB Domain (152-161) is Staphylococcal Enterotoxin B domain amino acid residue 152-161. | ||
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