About 3 results found for searched term "HPK1-IN-7" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10832 | HPK1-IN-7 | MAPKAPK2/MAP3K/MAP4K |
| HPK1-IN-7 is a potent inhibitor of the orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) (IC50=2.6 nM), with excellent family and kinase group selectivity. The HPK1-IN-7 is selective for IRAK4 (59 nM) and GLK (140 nM). HPK1-IN-7 combined with anti-PD1 has shown powerful efficacy in MC38 cogenic tumor models. | ||
| M42140 | HPK1-IN-37 | MAPKAPK2/MAP3K/MAP4K |
| HPK1-IN-37 is an inhibitor of HPK1 (IC50=3.7 nM). | ||
| M42133 | HPK1-IN-33 | MAPKAPK2/MAP3K/MAP4K |
| HPK1-IN-33 is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a Ki value of 1.7 nM. | ||
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