About 2 results found for searched term "HPI-4" (0.182 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6149 | HPI-4 | Hedgehog |
| Hedgehog Pathway Inhibitor 4 | ||
| HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. | ||
| M28147 | HPi1 | Antibiotic |
| HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum. | ||
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