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HPi1 

Cat. No. M28147

All AbMole products are for research use only, cannot be used for human consumption.

HPi1  Structure

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Quality Control & Documentation
Biological Activity

HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum.

Chemical Information
Molecular Weight 192.24
Formula C8H8N4S
CAS Number 13080-21-2
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Swati Mishra, et al. Sci Rep. Targeted delivery of harmine to xenografted human pancreatic islets promotes robust cell proliferation

[2] Ekaterina Gavrish, et al. Antimicrob Agents Chemother. In vitro and in vivo activities of HPi1, a selective antimicrobial against Helicobacter pylori

[3] Guozheng Liu, et al. Nucl Med Biol. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody

[4] Guozheng Liu, et al. Mol Pharm. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model

[5] Y Prigent, et al. Reprod Nutr Dev. Immunoelectron microscopic visualization of intermediate basic proteins HPI1 and HPI2 in human spermatids and spermatozoa

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  Catalog
Abmole Inhibitor Catalog




Keywords: HPi1  supplier, Antibiotic, inhibitors, activators

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