About 2 results found for searched term "GSK583" (0.215 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5232 | GSK583 | RIPK |
| GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM. | ||
| M31419 | JNJ-28583113 | TRP Channel |
| JNJ-28583113 is a brain-permeable TRPM2 antagonist and blocks phosphorylation of GSK3α and β subunits by inhibiting TRPM2. In addition, JNJ-28583113 inhibits cytokine release from microglia in response to pro-inflammatory stimuli. It has the function of protecting cells from oxidative stress-induced cell death. | ||
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