About 2 results found for searched term "GSK205" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7627 | BIO | GSK-3 |
| 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime6BIO; GSK 3 IX; GSK 3 Inhibitor IX; MLS 2052 | ||
| BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific GSK-3 inhibitor, the IC50 acting on GSK-3α/β in cell-free assays is 5 nM, which is more than 16 times more selective than ACTing on CDK5. It is also a pan-JAK inhibitor with an IC50 value of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells. | ||
| M14279 | GSK205 | TRP Channel |
| GSK205 is a potent, selective TRPV4 antagonist with an IC50 of 4.19 μM for inhibiting TRPV4-mediated Ca2+ influx. | ||
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