About 3 results found for searched term "GL189" (0.121 seconds)
Cat.No. | Name | Target |
---|---|---|
M20997 | Remogliflozin etabonate (GSK189075) | SGLT |
Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity inhibitor of sodium glucose cotransporter (SGLT2) with Ki of 1950 nM, 2140 nM, 43100 nM, 8570 nM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models. | ||
M52421 | GL189 | Gamma-secretase/Beta-secretase |
GL189 is a β-secretase inhibitor. | ||
M1923 | Lonidamine | CFTR |
AF 1890;Diclondazolic Acid; DICA | ||
Lonidamine (AF-1890) is a novel CFTR open channel blocker with an IC50 of 0.85 mM, which inhibits aerobic glycolysis in cancer cells. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki=2.5 μM). |
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