About 9 results found for searched term "GB-6" (0.227 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4815 | Vigabatrin | GABA Receptor |
| VGB; γ-Vinyl-GABA; CAS# 68506-86-5 | ||
| Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. | ||
| M10879 | RGB-286638 | CDK |
| RGB-286638 is a potent CDK inhibitor that inhibits cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 activity,IC50 1, 2, 3, 4, 5 and 5 nM, respectively, and can inhibit GSK-3β, TAK1, Jak2 and MEK1.IC50 The values are 3, 5, 50, and 54 nM, respectively. | ||
| M13611 | RGB-286638 free base | CDK |
| RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM. | ||
| M20986 | GUANABENZ | Adrenergic Receptor |
| GBZ, GA, Wytensin, Wy-8678 | ||
| Guanabenz (GBZ, GA, Wytensin, Wy-8678) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action. | ||
| M25085 | Geptanolimab | PD-1/PD-L1 |
| APL-501; CBT-501; GB-226 | ||
| Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer. | ||
| M30608 | RGB-286147 | CDK |
| RGB-286147 is a selective and ATP-competitive CDK and CDK-related kinases (CRK) inhibitor with IC50 values ranging from 9-839 nM. RGB-286147 shows less active against other non-CDK/CRK kinases. RGB-286147 induces cell apoptosis, and exhibits anti-tumor activity. | ||
| M40692 | BGB-16673 | PROTAC |
| BGB-16673 is an orally active chimeric degradation-activating compound targeting BTK that degrades wild-type BTK and a variety of mutant BTKs, and can be used in studies related to B-cell malignancies as well as non-Hodgkin's lymphoma. | ||
| M41785 | GB-6 | Bombesin Receptor |
| GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). | ||
| M57289 | Recombinant Human ITGB1 (HEK293, C-6His) | Cytokines and Growth Factors |
| Integrin Beta-1; Integrin β-1; CD29 | ||
| Integrin β-1 (ITGB1) belongs to the integrin β chain family. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin. | ||
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