About 7 results found for searched term "FAK" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5347 | Y15 | FAK |
| FAK inhibitor Y15; FAK Inhibitor 14 | ||
| Y15 is a novel small molecule FAK phosphorylation inhibitor; specifically block phosphorylation of Y397-FAK and total phosphorylation of FAK. | ||
| M14875 | PROTAC FAK degrader 1 | PROTAC |
| PROTAC FAK degrader 1 is a selective and potent von Hippel-Lindau-based focal adhesion kinase (FAK) degrader with an IC50 of 6.5 nM, DC50 of 3 nM. | ||
| M22383 | FAK ligand-Linker Conjugate 1 | Others |
| FAK ligand-Linker Conjugate 1 | ||
| M29603 | FAK inhibitor 6 | FAK |
| Compound 26F not only optimized the effective inhibitory enzyme (ic50= 28.2 nm), but also showed relatively less cytotoxicity (ic50= 3.32 μ M) And induced MDA-MB-231 cell apoptosis in a dose-dependent manner, effectively blocking MDA-MB-231 cells in g0/g1 phase. | ||
| M43215 | Perisulfakinin | Others |
| Perisulfakinin, a satiety signaling neuropeptide, inhibits the activity of central neurons promoting general activity. | ||
| M43495 | FAK-IN-9 | FAK |
| FAK-IN-9 is a potent and orally active FAK inhibitor with an IC50 of 27.44 nM. | ||
| M43498 | FAK-IN-11 | FAK |
| FAK-IN-11 is a FAK inhibitor. | ||
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