About 3 results found for searched term "Ezetimibe" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M3499 | Ezetimibe | Autophagy |
SCH 58235 | ||
Ezetimibe (Zetia) is a beta-lactam analog that targets NPC1L1, thereby lowering blood cholesterol levels. In addition, Ezetimibe can prevent spinal cord injury by inhibiting apoptosis through activation of autophagy and modulation of the PI3K/AKT/mTOR signaling pathway, which can be used in studies related to spinal cord injury. | ||
M21431 | Ezetimibe ketone | Keap1-Nrf2 |
EZM-K | ||
Ezetimibe ketone (EZM-K) is a phase I metabolite of Ezetimibe. Ezetimibe is an NPC1L1 inhibitor, and Ezetimibe inhibits intestinal cholesterol absorption by preventing the absorption of cholesterol by the NPC1L1 protein. It is a potent Nrf2 activator. | ||
M29865 | Desfluoro-ezetimibe | Keap1-Nrf2 |
Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. |
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