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 About 2 results found for searched term "EMA401" (0.133 seconds)

Cat.No.  Name Target
M8987 EMA401 Angiotensin Receptor
Olodanrigan; PD-126055
EMA401 (also known as Olodanrigan and PD-126055) is a highly selective angiotensin AT2 antagonist.
M28171 Olodanrigan sodium Angiotensin Receptor
EMA401 sodium; PD-126055 sodium
Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.



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