About 2 results found for searched term "EMA401" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8987 | EMA401 | Angiotensin Receptor |
| Olodanrigan; PD-126055; (S)-EMA400 | ||
| EMA401 (also known as Olodanrigan and PD-126055) is a highly selective angiotensin AT2 antagonist. | ||
| M28171 | Olodanrigan sodium | Angiotensin Receptor |
| EMA401 sodium; PD-126055 sodium | ||
| Olodanrigan (EMA401) sodium is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. Olodanrigan sodium is under development as a neuropathic pain therapeutic agent. Olodanrigan sodium analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. | ||
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