About 3 results found for searched term "Deguelin" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6661 | Deguelin | Akt |
| (-)-Deguelin; (-)-cis-Deguelin | ||
| Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB. | ||
| M14141 | Tephrosin | EGFR/HER2 |
| Deguelinol I; Hydroxydeguelin | ||
| Tephrosin is a natural rotenoid which has potent antitumor activities. Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors. | ||
| M40293 | Dehydrodeguelin | Others |
| Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L. | ||
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