About 6 results found for searched term "Dasatinib" (0.096 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1701 | Dasatinib | Src-bcr-Abl |
| BMS-354825 | ||
| Dasatinib (BMS-354825) is a small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0 nM, respectively. | ||
| M5552 | Dasatinib HCl | Src-bcr-Abl |
| BMS 354825 hydrochloride | ||
| Dasatinib(BMS-354825) hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of ＜1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM. | ||
| M5553 | Dasatinib Monohydrate | Src-bcr-Abl |
| BMS-354825 Monohydrate | ||
| Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively. | ||
| M57186 | Hydroxymethyl dasatinib | Src-bcr-Abl |
| Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib, exhibits an IC50 of 46.7nM in K562 CML cells. | ||
| M57125 | Dasatinib carbaldehyde | Ligands for Target Protein for PROTAC |
| Dasatinib carbaldehyde (BMS-354825 carbaldehyde), the Dasatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER . | ||
| M56619 | Dasatinib metabolite M6 | Metabolite/Endogenous Metabolite |
| Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib. | ||
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