About 4 results found for searched term "Dasatinib" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1701 | Dasatinib | Src-bcr-Abl |
| BMS-354825 | ||
| Dasatinib (BMS-354825) is a small molecule inhibitor of both the SRC and BCR/ABL tyrosine kinases, with IC50's for the isolated kinases of 0.55 and 3.0 nM, respectively. | ||
| M5552 | Dasatinib HCl | Src-bcr-Abl |
| BMS 354825 hydrochloride | ||
| Dasatinib(BMS-354825) hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of ＜1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM. | ||
| M5553 | Dasatinib Monohydrate | Src-bcr-Abl |
| BMS-354825 Monohydrate | ||
| Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively. | ||
| M29369 | SNIPER(ABL)-039 | PROTAC |
| SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, cIAP1, cIAP2, XIAP, respectively. | ||
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