About 10 results found for searched term "DHODH-IN-4" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54614 | hDHODH-IN-4 | DHODH |
| hDHODH-IN-4 is a potent inhibitor of human dihydroorotic acid dehydrogenase (DHODH) with a pIC50 of 7.8 for inhibition of human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8. hDHODH-IN-4 is a potent inhibitor of human recombinant DHODH. | ||
| M54625 | DHODH-IN-14 | DHODH |
| DHODH-IN-14 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 0.49 μM for hepatic DHODH in rats.DHODH-IN-14 can be used in rheumatoid arthritis-related studies. | ||
| M54624 | DHODH-IN-4 | DHODH |
| DHODH-IN-4 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor of human and Plasmodium falciparum, with IC50 values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively.DHODH-IN-4 exhibits anti-malarial activity. | ||
| M22180 | DSM265 | DHODH |
| DSM265 is a long-acting inhibitor of Plasmodium falciparum dihydroorotic acid dehydrogenase (PfDHODH) with an IC50 value of 8.9 nM. In addition, DSM265 inhibits the growth of Pf3D7 with an EC50 value of 4.3 nM. | ||
| M28093 | DHODH-IN-11 | DHODH |
| DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | ||
| M54626 | DHODH-IN-8 | DHODH |
| DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotic acid dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM and Ki of 0.016 μM and 5.6 μM, respectively.DHODH-IN-8 exhibits antimalarial activity. | ||
| M54616 | DHODH-IN-17 | DHODH |
| DHODH-IN-17 is a 2-anilinoylnicotinic acid and an inhibitor of human dihydroorotic acid dehydrogenase (DHODH) (IC50=0.40 μM).DHODH-IN-17 can be used in studies related to acute myeloid leukemia (AML). | ||
| M54630 | DHODH-IN-13 | DHODH |
| DHODH-IN-13 is a hydroxyfurazan analog of A771726 and a dihydroorotic acid dehydrogenase (DHODH) inhibitor with an IC50 of 4.3 μM for hepatic DHODH in rats.DHODH-IN-13 can be used in rheumatoid arthritis-related studies. | ||
| M54622 | hDHODH-IN-7 | DHODH |
| hDHODH-IN-7 is a human dihydroorotic acid dehydrogenase (DHODH) inhibitor with concomitant antiviral activity and a pMIC50 of 7.4. | ||
| M54612 | hDHODH-IN-13 | DHODH |
| hDHODH-IN-13 is an inhibitor of human dihydroorotic acid dehydrogenase (hDHODH) with an IC50 value of 173.4 nM. hDHODH-IN-13 can be used in studies related to inflammatory bowel disease (IBD). | ||
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