About 11 results found for searched term "DAR-1" (0.068 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1845 | LY335979 trihydrochloride | P-glycoprotein |
| Zosuquidar trihydrochloride; RS 33295-198 trihydrochloride | ||
| LY335979 (Zosuquidar trihydrochloride) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M2028 | Fludarabine | STAT |
| Fludara; NSC 118218; Fludarabinum; F-ara-A | ||
| Fludarabine (NSC 118218) is a STAT1 activation inhibitor and a DNA synthesis inhibitor. Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. Fludarabine markedly inhibited VSMC proliferation in cell culture. Fludarabine also induces significant reduction of STAT-1 phosphorylation, whereas it does not change JAK2 activation. Fludarabine exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. | ||
| M5609 | Elacridar (GF120918) | P-glycoprotein |
| GW120918; GG918 | ||
| Elacridar (GF120918) is a potent P-gp (MDR-1) and BCRP inhibitor. | ||
| M27996 | Dihydrexidine | Dopamine Receptor |
| DAR-0100 | ||
| Dihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor. Dihydrexidine exhibits potent antiparkinsonian activity. Dihydrexidine can stimulate YAP phosphorylation. | ||
| M28278 | Dihydrexidine hydrochloride | Dopamine Receptor |
| DAR-0100 hydrochloride | ||
| Dihydrexidine hydrochloride (DAR-0100 hydrochloride) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist, with an IC50 of 10 nM for D1 receptor. Dihydrexidine hydrochloride exhibits potent antiparkinsonian activity. Dihydrexidine hydrochloride can stimulate YAP phosphorylation. | ||
| M39697 | 15-Isopimarene-8,18-diol | Others |
| 8β,18-Dihydroxysandaracopimar-15-ene | ||
| 15-Isopimarene-8,18-diol (8β,18-Dihydroxysandaracopimar-15-ene) is a compound isolated from Thuja orientalis. | ||
| M40832 | RAS-IN-2 | Ras |
| RMC-6236; Daraxonrasib; RAS Inhibitor A122 | ||
| RAS-IN-2 (RMC-6236) is a potent pan-KRAS inhibitor targeting activation-state KRAS for cancer-related studies. | ||
| M42206 | GluN2B-NMDAR antagonist-1 | GluR |
| GluN2B-NMDAR antagonist-1 is an orally active GluN2B-NMDAR antagonist. | ||
| M52984 | [DAla2, DArg6] Dynorphin A, (1-13) (porcine) | Opioid Receptor |
| [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. | ||
| M55385 | DAR-1 | Fluorescent Dye |
| 4,5-Diamino-N,N,N',N'-tetraethyl-rhodamin; Fluorescent NO probe | ||
| DAR-1 is a sensitive fluorescent NO probe. | ||
| M56500 | NMDAR antagonist 1 | GluR |
| NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective NMDAR antagonist. | ||
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