About 4 results found for searched term "Cyclosporine" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1831 | Cyclosporine A | Immunology/Inflammation |
| Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1 | ||
| Cyclosporine A (CsA，Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. | ||
| M20393 | Cyclosporine | Phosphatase |
| Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. | ||
| M31399 | Rencofilstat | Cyclophilin |
| RCF; CRV431 | ||
| Rencofilstat (CRV431) is a cyclosporine derivative as well as an orally active cycloheximide (CYPA) inhibitor for studies related to non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma. | ||
| M53436 | Dihydrocyclosporin A | Parasite |
| Dihydrocyclosporin A is a derivative of Cyclosporine A. | ||
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