About 6 results found for searched term "Cyclopamine" (0.166 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1975 | Cyclopamine | Hedgehog |
| 11-deoxojervine | ||
| Cyclopamine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. | ||
| M3995 | Jervine | Hedgehog |
| 11-Ketocyclopamine | ||
| Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. | ||
| M11272 | KAAD-Cyclopamine | Smo |
| Cyclopamine-KAAD | ||
| Kaad-cyclopamine is an inhibitor of hedgehog signaling pathway and an antagonist of Smoothened. | ||
| M14928 | SAG | Smo |
| SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. | ||
| M14929 | SAG dihydrochloride | Smo |
| SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. | ||
| M28245 | MRT-83 hydrochloride | Smo |
| MRT-83 (hydrochloride) is the potent antagonist of Smoothened (Smo) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease. | ||
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