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Jervine inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in a number of experimental models.
| Molecular Weight | 425.6 |
| Formula | C27H39NO3 |
| CAS Number | 469-59-0 |
| Solubility (25°C) | DMSO 5mg/ml Ethanol 10mg/ml |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Blane P Zavesky, et al. Progress toward a Convergent, Asymmetric Synthesis of Jervine
| Related Hedgehog Products |
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| Hedgehog IN-3
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