About 3 results found for searched term "Crizotinib" (0.291 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1765 | Crizotinib | c-Met |
| PF-02341066 | ||
| Crizotinib (PF-02341066) is a potent, orally bioavailable, ATP-competitive small-molecule inhibitor of c-Met kinase and ALK (anaplastic lymphoma kinase) with IC50 values to be 4 and 25 nM for C-Met and ALK resepectively. | ||
| M2350 | (S)-crizotinib | MTH1 |
| (S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM. | ||
| M5320 | Crizotinib hydrochloride | ALK |
| PF-02341066 hydrochloride | ||
| Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is useful in treatment of anaplastic large-cell lymphoma. | ||
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