About 3 results found for searched term "Cpd 8" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11195 | CDDO-2-P-Im | Apoptosis |
| CPD1589;CPDB1589 | ||
| Cddo-2p-im is a CDDO imidazolid analogue with chemoprophylaxis. Cddo-2p-im reduced the size and severity of lung tumors in mouse lung cancer models. Cddo-2p-im is an orally active necroptosis inhibitor that can be used in ischemia/reperfusion (I/R) studies. | ||
| M30649 | C188 | STAT |
| CPD188 | ||
| C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro (EC50= 0.7 μM). | ||
| M49360 | Cpd 8 | RIPK |
| Cpd 8 is a type II RIPK1 inhibitor that binds to the ATP site in the inactive conformation of the kinase. | ||
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