About 7 results found for searched term "Clozapine" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3417 | Clozapine | 5-HT Receptor |
| HF 1854 | ||
| Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. | ||
| M7684 | Clozapine N-oxide | 5-HT Receptor |
| CNO | ||
| Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC. | ||
| M11551 | Deschloroclozapine | AChR/AChE |
| Deschloroclozapine is an effective, high affinity, selective, metabolically stable agonist based on muscarinic DREADDs. The Ki binding values of Deschloroclozapine to DREADD receptor subtypes hM3Dq and hM4Di were 6.3 and 4.2 nM, respectively. | ||
| M14003 | Clozapine N-oxide dihydrochloride | AChR/AChE |
| Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. | ||
| M30363 | N-Desmethylclozapine | AChR/AChE |
| Norclozapine; Desmethylclozapine; Normethylclozapine | ||
| N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist. | ||
| M55456 | Clozapine-d8 | 5-HT Receptor |
| Clozapine-d8 | ||
| M55457 | N-Desmethyl Clozapine-d8 | Others |
| N-Desmethyl Clozapine-d8 | ||
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