About 4 results found for searched term "CZ-48" (0.3 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2609 | CZC24832 | PI3K |
| CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ. | ||
| M58990 | CZ-48 | TLR |
| Sulfo-ara-F-NMN | ||
| CZ-48 (Sulfo-ara-F-NMN) is a mimetic of nicotinamide mononucleotide (NMN). CZ-48 acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). CZ-48 induces intracellular cyclic ADP-ribose (cADPR) production. | ||
| M29040 | Camptothecin-20(S)-O-propionate | Topoisomerase |
| Camptothecin-20-O-propionate | ||
| Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor. | ||
| M42305 | TSC25 | Cathepsin |
| TSC25 is a potent cruzipain (CZP) inhibitor, with an IC50 of 3.34 nM and a pIC50 of 8.48. | ||
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