About 4 results found for searched term "CYC116" (0.223 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1694 | CYC116 | Aurora Kinase |
| CYC116 is a potent, small molecule inhibitor of Aurora A, B and C with IC50 value of 44, 19 and 65 nM respectively. | ||
| M21040 | BSJ-4-116 | CDK |
| BSJ-4-116 is a specific degrader of cyclin-dependent kinase 12 (CDK12). BSJ-4-116 exhibits potent antiproliferative effects. | ||
| M28071 | S116836 | Src-bcr-Abl |
| S116836, a potent, orally active BCR-ABL tyrosine kinase inhibitor, blocks both wild-type as well as T315I Bcr-Abl. S116836 arrests the cells in the G0/G1 phase of cell cycle, induces apoptosis, increases ROS production, and decreases GSH production in BaF3/WT and BaF3/T315I cells. S116836 also inhibits SRC, LYN, HCK, LCK and BLK, and receptor tyrosine kinases such as FLT3, TIE2, KIT, PDGFR-β. Antitumor activies. | ||
| M44825 | Cyclo(L-Ala-L-Pro) | Others |
| Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2. | ||
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