CTP Inhibitor - Search Results

About 6 results found for searched term "CTP Inhibitor" (0.129 seconds)

Cat.No.	Name	Target
M8219	CTP Inhibitor	Others
	CTP Inhibitor is an inhibitor of mitochondrial citrate transport protein, was the first purely competitive inhibitor to be discovered and is more potent than BTC.
M1724	CTP-518	Proteasome
	CTP-518 is a novel HIV protease inhibitor. CTP-518 has the potential to be the first HIV protease inhibitor toeliminate the need to co-dose with a boosting agent.
M20774	CTPI-2	Mitochondrial Related
	CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with KD of 3.5 μM. CTPI-2 is a unique regulator of glycolysis that limits the metabolic plasticity of cancer stem cells (CSCs).
M28961	TH1217	Anti-infection
	ZINC1775962367
	TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19.
M52368	CTP-NBD	NF-κB
	CTP-NBD is a cell permeable specific NFκB peptide inhibitor.
M55967	CTP Synthetase-IN-1	DNA/RNA Synthesis
	CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively.