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CTP Inhibitor

Cat. No. M8219

All AbMole products are for research use only, cannot be used for human consumption.

CTP Inhibitor Structure

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Quality Control & Documentation
Biological Activity

CTP Inhibitor is an inhibitor of mitochondrial citrate transport protein, was the first purely competitive inhibitor to be discovered and is more potent than BTC.

Chemical Information
Molecular Weight 356.74
Formula C13H9ClN2O6S
CAS Number 412940-35-3
Solubility (25°C) DMSO: ≥23 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gregory D McCluskey, et al. Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5'-Triphosphate

[2] Paul Lee, et al. Current Phase II proprotein convertase subtilisin/kexin 9 inhibitor therapies for dyslipidemia

[3] Tatsuhiko Yoshida, et al. Discovery of a compound that acts as a bacterial PyrG (CTP synthase) inhibitor

[4] J R Wild, et al. In the presence of CTP, UTP becomes an allosteric inhibitor of aspartate transcarbamoylase

[5] S W Fesik, et al. NMR methods for determining the structures of enzyme/inhibitor complexes as an aid in drug design

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Keywords: CTP Inhibitor supplier, inhibitors, activators

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