About 3 results found for searched term "CHD-5" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8310 | CHD-5 | Others |
| CHD-5 is a potent aryl hydrocarbon receptor antagonist. | ||
| M28730 | CHDI-390576 | HDAC |
| CHDI-390576, a potent, cell permeable and CNS penetrant class IIa histone deacetylase (HDAC) inhibitor with IC50s of 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9, respectively, shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity over HDAC8 and the class IIb HDAC6 isoform. | ||
| M29776 | CHD1Li 6.11 | Others |
| CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties. | ||
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