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CHD1Li 6.11 

Cat. No. M29776

All AbMole products are for research use only, cannot be used for human consumption.

CHD1Li 6.11  Structure

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Quality Control & Documentation
Biological Activity

CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties.

Chemical Information
Molecular Weight 472.4
Formula C21H22BrN5OS
CAS Number 2716890-91-2
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brett J Prigaro, et al. J Med Chem. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

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Keywords: CHD1Li 6.11  supplier, inhibitors, activators

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