About 4 results found for searched term "CFM-2" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5081 | CFM-2 | GluR |
| CFM-2 is a selective non-competitive AMPAR antagonist. | ||
| M28057 | JTE-952 | CSF-1R (c-Fms) |
| JTE-952 is a potent, oral active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis. | ||
| M29925 | CFM-4 | Apoptosis |
| CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells. | ||
| M30738 | CFMTI | GluR |
| CFMTI inhibits L-glutamate-induced intracellular Ca2+ mobilization in CHO cells expressing human and rat mGluR1a, with IC50s of 2.6 and 2.3 nM, respectively. | ||
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