About 4 results found for searched term "CB1-IN-1" (0.11 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5944 | Ruxolitinib phosphate | JAK |
| INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate; Ruxolitinib | ||
| Ruxolitinib phosphate(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. | ||
| M9652 | CB1-IN-1 | Cannabinoid |
| DBPR211; BPRCB1184 | ||
| CB1-IN-1 is a novel potent restricted CB1R antagonist with Ki of 0.3 nM and 21 nM for CB1R and CB2R, respectively. | ||
| M14069 | Numidargistat dihydrochloride | Others |
| CB-1158 dihydrochloride; INCB01158 dihydrochloride | ||
| Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent. | ||
| M42232 | ABCB1-IN-1 | P-glycoprotein |
| ABCB1-IN-1 is a potent ABCB1 inhibitor. | ||
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