About 2 results found for searched term "Banoxantrone" (0.509 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8702 | Banoxantrone dihydrochloride | Topoisomerase |
| AQ4N dihydrochloride | ||
| Banoxantrone (AQ4N) is a precursor compound of the hypoxic-activated topoisomerase II inhibitor AQ4(bioreduced AQ4 precursor). | ||
| M28261 | Banoxantrone | NO Synthase |
| AQ4N | ||
| Banoxantrone (AQ4N), as a prototype hypoxia selective cytotoxin, can be reduced to AQ4, a potent topoisomerase II inhibitor. Banoxantrone selectively kills hypoxic cells via an iNOS-dependent mechanism. Banoxantrone shows a potent cytotoxicity and hypoxia-selective effect enhanced by radiation. | ||
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