About 15 results found for searched term "BT-13" (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6830 | INH1 | Others |
| IBT13131 | ||
| INH1 is a hec1 inhibitor; causes arrest of mitosis. | ||
| M10944 | BT-13 | Others |
| BT-13 is a potent, glial-derived neurotrophic factor (GDNF) receptor RET selective agonist (independent of GDNF ligands) that promotes the growth of process ninsters in vitro sensory neurons and mitigates the occurrence of neuropathy in rats. | ||
| M43147 | BTB01303 | Others |
| BTB01303 is a (glutamate release) inhibitor. | ||
| M2601 | Walrycin B | Antibiotic |
| Walrycin-B | ||
| Walrycin B is a novel antibiotic that can specifically target the WalR response regulator with IC50 of 0.39ug/mL (MIC for B. Subtilis 168) and 3.13ug/mL (MIC for S. aureus N315), respectively. | ||
| M10791 | BAY-1316957 | Prostaglandin Receptor |
| BAY-1316957 is a potent, selective, orally active antagonist of the prostaglandin E2 receptor subtype 4 (EP4-R) against human EP4-R IC50 15.3 nM. BAY-1316957 has excellent drug metabolism and pharmacokinetic properties and can be used in the study of endometriosis. | ||
| M18258 | 11beta,13-Dihydrolactucin | Immunology/Inflammation |
| 11beta,13-Dihydrolactucin is a sesquiterpene lactone obtained by formal hydrogenation across the 11,13-double bond of lactucin. Found in chicory It has a role as a plant metabolite. | ||
| M24956 | Cendakimab | IL Receptor/Related |
| RPC 4046; ABT 308; CC-93538 | ||
| Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. | ||
| M28688 | PF-06372865 | GABA Receptor |
| Darigabat | ||
| PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABAA positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABAA receptors containing α1/α2/α3/α5 subunits (Kis of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy. | ||
| M30578 | VU0134992 | Potassium Channel |
| VU0134992 is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV. | ||
| M30952 | Lck inhibitor 2 | Src-bcr-Abl |
| Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively IC50 Value: 13 nM(Lck) [1] Target: Src family kinase Lck inhibitor 2(Compound 9) inhibited 48 kinases with %control < 1 (33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel). A further 27 kinases were bound with %control < 10. Kd values for 16 kinases were determined and found to be below 100 nM. These included TXK (10 nM). | ||
| M38654 | 4-Methylherniarin | Antibiotic |
| 4-Methylherniarin (7-Methoxy-4-methylcoumarin) has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 ug/ml and 13.47 ug/ml. | ||
| M41901 | PSB-1114 triethylamine | P2 Receptor |
| PSB-1114 triethylamine is a potent, enzymatically stable, and subtype-selective P2Y2 receptor agonist with an EC50 of 134 nM. | ||
| M49909 | ML230 | BCRP/ABCG2/MXR/ABCP |
| CID44640177; SID 88095709 | ||
| ML230 is a selective inhibitor of the ATP-binding transporter subtype ABCG2, and its inhibitory effect on ABCG2 was 36 times that of ABCB1, with EC50 values of 0.13 μM and 4.65 μM, respectively. | ||
| M55233 | CVN293 | Potassium Channel |
| CVN293 is a selective and brain permeable potassium (K+) ion channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. | ||
| M56303 | PSB-1114 tetrasodium | P2 Receptor |
| PSB-1114 tetrasodium is a potent, enzymatically stable, and subtype-selective P2Y2 receptor agonist with an EC50 of 134 nM. | ||
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