BMS-8 - Search Results | AbMole BioScience

About 5 results found for searched term "BMS-8 " (0.053 seconds)

Cat.No.	Name	Target
M28672	BMS-986118	GPR/FFAR
	BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models.
M28797	BMS-8	PD-1/PD-L1
	BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1.
M28848	BMS-986188	Opioid Receptor
	BMS-986188 is a selective positive allosteric modulator of δ-opioid receptor with an EC50 of 0.05 μM.
M30378	BMS-585248	HIV Protease
	BMS-585248 is a potent, third-generation HIV-1 attachment inhibitor with a promising initial in vitro and in vivo pharmacokinetic profile.
M56558	BMS-986308	Potassium Channel
	BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor.