About 1 result found for searched term "BI-671800" (0.132 seconds)
Cat.No. | Name | Target |
---|---|---|
M20981 | BI-671800 | Prostaglandin Receptor |
AP-761, Cmpd A | ||
BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS. |
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