About 13 results found for searched term "BCH" (0.061 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3352 | Lamivudine (BCH-189) | Reverse Transcriptase |
| BCH-189 | ||
| Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) with an IC50 of 2.7 mM. Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS. | ||
| M11527 | BCH001 | DNA/RNA Synthesis |
| 3-Quinolinecarboxylic acid | ||
| BCH001 is a quinoline derivative and a selective PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in pluripotent stem cells induced by congenital keratosis (DC). BCH001 did not inhibit poly (A) -specific ribonucase (PARN) or several other polynucleotide polymerases. PAPD5 is A nonnormalized Poly (A) polymerase with an unconventional RNA binding motif. | ||
| M20862 | BCH | Others |
| 2-Aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, LAT1-IN-1 | ||
| BCH (2-Aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, LAT1-IN-1) is a selective and competitive inhibitor of system L amino acid transporter 1 (LAT1). BCH (LAT1-IN-1) induces apoptosis in cancer cells. | ||
| M41485 | BChE/HDAC6-IN-1 | HDAC |
| BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. | ||
| M41607 | BChE/HDAC6-IN-2 | Tau Protein |
| BChE/HDAC6-IN-2 is a dual inhibitor of BChE and HDAC6 with IC50s of 1.8 nM and 71.0 nM, respectively. | ||
| M42640 | BChE-IN-19 | AChR/AChE |
| BChE-IN-19 is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). | ||
| M42642 | BChE-IN-17 | AChR/AChE |
| BChE-IN-17 is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. | ||
| M42644 | hBChE-IN-2 | AChR/AChE |
| hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. | ||
| M42653 | AChE/BChE-IN-15 | AChR/AChE |
| AChE/BChE-IN-15 is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively. | ||
| M42654 | AChE/BChE-IN-12 | AChR/AChE |
| AChE/BChE-IN-12 inhibitor, with IC50 values of 2.57, 3.26, and 10.65 μM, respectively. | ||
| M42656 | BChE-IN-16 | AChR/AChE |
| BChE-IN-16 is a highly potent BChE inhibitor with an IC50 of 3.8 nM for hBChE. | ||
| M42669 | hBChE-IN-1 | AChR/AChE |
| hBChE-IN-1 and highly selective over hAChE. | ||
| M58958 | Butyryl Cholinesterase (Horse serum) | Enzymes & Coenzymes |
| BuChE; BChE | ||
| Butyryl Cholinesterase is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE) but has different substrate specificity and inhibitor sensitivity. The enzyme is a tetrameric glycoprotein composed of four identical subunits (110 kDa each) and is also known as pseudocholinesterase. It is synthesised in the liver and distributed in blood, neuromuscular junction synapses, glial cells and white matter axons. | ||
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