About 8 results found for searched term "BC-05" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5884 | Pizotifen | 5-HT Receptor |
| Pizotyline; BC-105 | ||
| Pizotifen (Pizotyline) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. | ||
| M14941 | Tegatrabetan | Wnt/beta-catenin |
| BC2059 | ||
| Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1). | ||
| M24806 | Sampeginterferon beta-1a | Others |
| BCD-054 | ||
| Sampeginterferon beta-1a (BCD-054) is a pegylated IFNβ-1a. Sampeginterferon beta-1a can be used for research against remitting multiple sclerosis. | ||
| M42532 | BC-05 | Others |
| BC-05 is an orally active and potent inhibitor of CD13 and proteasome. | ||
| M29637 | PF-07059013 | Others |
| PF-07059013 is an orally active and potent noncovalent modulator of sickled hemoglobin (HbS). PF-07059013 specifically binds to Hb with nanomolar affinity and displays strong partitioning into red blood cells (RBCs). PF-07059013 can be used for sickle cell disease (SCD) research. | ||
| M29662 | Stellasterol | Glucosidase |
| Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor. | ||
| M30939 | CAY10526 | PGE synthase |
| CAY10526 is a specific microsomal PGE2 synthase-1 (mPGES1) inhibitor. CAY10526 inhibits PGE2 production through the selective modulation of mPGES1 expression but does not affect COX-2. CAY10526 significantly suppresses tumor growth and increases apoptosis in melanoma xenografts. CAY10526 reduces BCL-2 and BCL-XL (anti-apoptotic) protein levels and increases BAX and BAK (pro-apoptotic) as well as cleaved caspase 3 levels. CAY10526 inhibits cell viability (IC50<5 μM) in three melanoma cell lines expressing mPGES1. | ||
| M43927 | SGR-1505 | MALT1 |
| SGR1505 | ||
| SGR-1505 is an oral potent small molecule allosteric inhibitor of MALT1 that inhibits MALT1 enzymatic activity and demonstrates anti-proliferative activity in ABC-DLBCL cell lines, both BTKi-sensitive (OCI-LY10) and BTKi-resistant (OCI-LY3). SGR-1505 can be used in studies related to B-cell tumors. | ||
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