About 13 results found for searched term "B 746" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1972 | Iniparib | PARP |
| BSI-201, NSC-746045, IND-71677 | ||
| Iniparib is an irreversible, noncompetitive inhibitor of PARP1 that disrupts binding between PARP1 and DNA by interacting with the DNA binding domain. | ||
| M2791 | Vilazodone hydrochloride | 5-HT Receptor |
| EMD 68843; SB659746A | ||
| KALA peptide binds oligonucleotides and disrupts cell membrane; therefore, it can be used as a DNA transfection reagent. | ||
| M3160 | Vilazodone | 5-HT Receptor |
| EMD 68843, SB 659746A | ||
| Verazodone (EMD 68843; SB 659746A) is a complex serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently being evaluated in clinical studies for major depression. | ||
| M41044 | B 746 | Antibiotic |
| B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin. | ||
| M5346 | WZ3146 | EGFR/HER2 |
| WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I). | ||
| M13532 | S55746 | Bcl-2 |
| BCL201 | ||
| S55746 (BCL201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BCL201) has antitumor activity with low toxicity. | ||
| M13533 | S55746 hydrochloride | Bcl-2 |
| BCL201 hydrochloride | ||
| S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity. | ||
| M14939 | β-catenin-IN-2 | Wnt/beta-catenin |
| β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1. β-catenin-IN-2 can be used for the study of colorectal cancer. | ||
| M15078 | Recombinant Mouse Noggin/NOG (HEK293,C-6His) | Cytokines and Growth Factors |
| Noggin; Nog | ||
| Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466. | ||
| M27689 | PF-03654746 Tosylate | Histamine Receptor |
| PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD). | ||
| M30812 | S-777469 | Cannabinoid |
| S-777469 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism. | ||
| M30935 | PF-03654746 | Histamine Receptor |
| PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 reduces allergen-induced nasal symptoms, might be a novel therapeutic strategy to further explore allergic rhinitis. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD). | ||
| M53913 | Smcy HY Peptide (738-746) | Others |
| Smcy HY Peptide (738-746) is a H2-Db-restricted peptide corresponding to amino acids 738-746 of Smcy protein. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
